Life-threatening flecainide overdose treated with intralipid and extracorporeal membrane oxygenation.

Authors :: Brumfield E
Bernard KR
Kabrhel C
Source :: The American journal of emergency medicine [Am J Emerg Med] 2015 Dec; Vol. 33 (12), pp. 1840.e3-5. Date of Electronic Publication: 2015 Apr 12.
Publication Year :: 2015
Abstract: Flecainide is a Class Ic antiarrythmic agent associated with adverse events due to its pro-arrythmic effects. We report the case of a 33-year-old female presenting in cardiac arrest after a flecainide overdose treated with intravenous fat emulsion (IFE), sodium bicarbonate (NaHCO₃), and extracorporeal membrane oxygenation (ECMO). This case reviews the pathophysiology and management of flecainide toxicity including novel strategies of IFE and ECMO.

Subjects :: Adult
Electrocardiography
Fat Emulsions, Intravenous therapeutic use
Female
Heart Arrest therapy
Humans
Sodium Bicarbonate therapeutic use
Anti-Arrhythmia Agents poisoning
Drug Overdose therapy
Extracorporeal Membrane Oxygenation
Flecainide poisoning
Heart Arrest chemically induced

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