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A novel multidisciplinary intervention for long-term weight loss and glycaemic control in obese patients with diabetes.
- Source :
-
Journal of diabetes research [J Diabetes Res] 2015; Vol. 2015, pp. 729567. Date of Electronic Publication: 2015 Apr 08. - Publication Year :
- 2015
-
Abstract
- Introduction: Obesity and diabetes are difficult to treat in public clinics. We sought to determine the effectiveness of the Metabolic Rehabilitation Program (MRP) in achieving long-term weight loss and improving glycaemic control versus "best practice" diabetes clinic (DC) in obese patients using a retrospective cohort study.<br />Methods: Patients with diabetes and BMI > 30 kg/m(2) who attended the MRP, which consisted of supervised exercise and intense allied health integration, or the DC were selected. Primary outcomes were improvements in weight and glycaemia with secondary outcomes of improvements in blood pressure and lipid profile at 12 and 30 months.<br />Results: Baseline characteristics of both cohorts (40 MRP and 40 DC patients) were similar at baseline other than age (63 in MRP versus 68 years in DC, P = 0.002). At 12 months, MRP patients lost 7.65 ± 1.74 kg versus 1.76 ± 2.60 kg in the DC group (P < 0.0001) and 9.70 ± 2.13 kg versus 0.98 ± 2.65 kg at 30 months (P < 0.0001). Similarly, MRP patients had significant absolute reductions in %HbA1c at 30 months versus the DC group (-0.86 ± 0.31% versus 0.12% ± 0.33%, P < 0.038), with nonsignificant improvements in lipids and blood pressure in MRP patients.<br />Conclusion: Further research is needed to establish the MRP as an effective strategy for achieving sustained weight loss and improving glycaemic control in obese patients with type 2 diabetes.
- Subjects :
- Aged
Blood Pressure
Body Weight
Diabetes Mellitus, Type 2 blood
Diabetes Mellitus, Type 2 complications
Female
Humans
Lipids blood
Male
Middle Aged
Obesity blood
Obesity complications
Retrospective Studies
Treatment Outcome
Weight Loss
Blood Glucose metabolism
Diabetes Mellitus, Type 2 therapy
Diet, Reducing
Exercise Therapy
Hypoglycemic Agents therapeutic use
Obesity therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2314-6753
- Volume :
- 2015
- Database :
- MEDLINE
- Journal :
- Journal of diabetes research
- Publication Type :
- Academic Journal
- Accession number :
- 25950007
- Full Text :
- https://doi.org/10.1155/2015/729567