Gut microbes, immunity, and spondyloarthritis.

Authors :: Stoll ML
Source :: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2015 Aug; Vol. 159 (2), pp. 134-42. Date of Electronic Publication: 2015 May 09.
Publication Year :: 2015
Abstract: The last decade has witnessed an explosion of studies evaluating the impact of the human microbiota on a variety of disease states. The microbiota can impact diseases in multiple ways, including through abnormalities in the diversity and contents of the microbiota, as well as by acting as targets of immunologic dysregulation. Herein, evidence that the microbiota in spondyloarthritis is both altered and abnormally targeted by the immune system will be presented.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)