Back to Search
Start Over
Malignant metastasizing solitary fibrous tumors of the liver: a report of three cases.
- Source :
-
Polish journal of pathology : official journal of the Polish Society of Pathologists [Pol J Pathol] 2015 Mar; Vol. 66 (1), pp. 72-6. - Publication Year :
- 2015
-
Abstract
- Solitary fibrous tumors are rare neoplasms of mesenchymal origin that have been reported in various other extrathoracic sites, including the liver. We present a case series of three malignant solitary fibrous tumors of the liver, occurring in two women 74 and 80 years old and one 65-year-old man. No clinical features were predictive of malignancy except the large sizes and synchronous presence of lung metastases in two of the three cases. Histological examinations revealed the presence of high pleomorphic cellularity with nuclear atypia, necrosis and high mitotic ratios. All patients died of disease progression.
- Subjects :
- Abdominal Neoplasms chemistry
Abdominal Neoplasms therapy
Aged
Aged, 80 and over
Biomarkers, Tumor analysis
Biopsy
Disease Progression
Fatal Outcome
Female
Humans
Immunohistochemistry
Liver Neoplasms chemistry
Liver Neoplasms therapy
Lung Neoplasms chemistry
Lung Neoplasms therapy
Male
Mitosis
Necrosis
Solitary Fibrous Tumors chemistry
Solitary Fibrous Tumors therapy
Time Factors
Tomography, X-Ray Computed
Tumor Burden
Abdominal Neoplasms secondary
Liver Neoplasms pathology
Lung Neoplasms secondary
Solitary Fibrous Tumors secondary
Subjects
Details
- Language :
- English
- ISSN :
- 1233-9687
- Volume :
- 66
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Polish journal of pathology : official journal of the Polish Society of Pathologists
- Publication Type :
- Academic Journal
- Accession number :
- 26017883
- Full Text :
- https://doi.org/10.5114/pjp.2015.51156