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Red Kidney: Kidney Transplant From a Deceased Donor Who Received Massive Blood Transfusion During Cardiopulmonary Bypass.

Authors :
Bell R
Hanif F
Prasad P
Ahmad N
Source :
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [Exp Clin Transplant] 2016 Jun; Vol. 14 (3), pp. 341-4. Date of Electronic Publication: 2015 May 30.
Publication Year :
2016

Abstract

Here, we present a case of a deceased-donor kidney transplant. The brain-dead donor had received a massive blood transfusion during cardiopulmonary bypass, which lead to hemolysis, hemoglobinuria, acute kidney injury, and renal replacement therapy. The kidney appeared red after in situ flush. Postoperatively, the recipient developed delayed graft function. Protocol biopsy during the postoperative period revealed the widespread deposition of heme pigment in the renal tubules. Massive blood transfusion and cardiopulmonary bypass surgery are associated with hemolysis and heme pigment deposition in the renal tubules, which subsequently lead to acute kidney injury. Kidneys from such donors appear red and, while this does not preclude transplant, are likely to develop delayed graft function.

Details

Language :
English
ISSN :
2146-8427
Volume :
14
Issue :
3
Database :
MEDLINE
Journal :
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Publication Type :
Academic Journal
Accession number :
26030717
Full Text :
https://doi.org/10.6002/ect.2014.0129