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Red Kidney: Kidney Transplant From a Deceased Donor Who Received Massive Blood Transfusion During Cardiopulmonary Bypass.
- Source :
-
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [Exp Clin Transplant] 2016 Jun; Vol. 14 (3), pp. 341-4. Date of Electronic Publication: 2015 May 30. - Publication Year :
- 2016
-
Abstract
- Here, we present a case of a deceased-donor kidney transplant. The brain-dead donor had received a massive blood transfusion during cardiopulmonary bypass, which lead to hemolysis, hemoglobinuria, acute kidney injury, and renal replacement therapy. The kidney appeared red after in situ flush. Postoperatively, the recipient developed delayed graft function. Protocol biopsy during the postoperative period revealed the widespread deposition of heme pigment in the renal tubules. Massive blood transfusion and cardiopulmonary bypass surgery are associated with hemolysis and heme pigment deposition in the renal tubules, which subsequently lead to acute kidney injury. Kidneys from such donors appear red and, while this does not preclude transplant, are likely to develop delayed graft function.
- Subjects :
- Acute Kidney Injury diagnosis
Acute Kidney Injury metabolism
Acute Kidney Injury therapy
Adult
Biopsy
Brain Death
Delayed Graft Function blood
Delayed Graft Function diagnosis
Hemoglobinuria etiology
Hemolysis
Humans
Kidney metabolism
Kidney pathology
Kidney Failure, Chronic diagnosis
Kidney Transplantation adverse effects
Male
Renal Dialysis
Treatment Outcome
Young Adult
Acute Kidney Injury etiology
Cardiopulmonary Bypass adverse effects
Delayed Graft Function etiology
Donor Selection
Heme metabolism
Kidney surgery
Kidney Failure, Chronic surgery
Kidney Transplantation methods
Tissue Donors
Transfusion Reaction
Subjects
Details
- Language :
- English
- ISSN :
- 2146-8427
- Volume :
- 14
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 26030717
- Full Text :
- https://doi.org/10.6002/ect.2014.0129