Chemistry for oncotheranostic gold nanoparticles.

Authors :: Trouiller AJ
Hebié S
El Bahhaj F
Napporn TW
Bertrand P
Source :: European journal of medicinal chemistry [Eur J Med Chem] 2015 Jun 24; Vol. 99, pp. 92-112. Date of Electronic Publication: 2015 May 20.
Publication Year :: 2015
Abstract: This review presents in a comprehensive ways the chemical methods used to functionalize gold nanoparticles with focus on anti-cancer applications. The review covers the parameters required for the synthesis gold nanoparticles with defined shapes and sizes, method for targeted delivery in tumours, and selected examples of anti-cancers compounds delivered with gold nanoparticles. A short survey of bioassays for oncology based on gold nanoparticles is also presented.<br /> (Copyright © 2015 Elsevier Masson SAS. All rights reserved.)