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Dehydrogenative [2 + 2 + 2] Cycloaddition of Cyano-yne-allene Substrates: Convenient Access to 2,6-Naphthyridine Scaffolds.

Authors :
Haraburda E
Lledó A
Roglans A
Pla-Quintana A
Source :
Organic letters [Org Lett] 2015 Jun 19; Vol. 17 (12), pp. 2882-5. Date of Electronic Publication: 2015 Jun 11.
Publication Year :
2015

Abstract

A rhodium-catalyzed [2 + 2 + 2] cycloaddition of cyano-yne-allene scaffolds followed by a dehydrogenative process enabling the direct synthesis of unsaturated pyridine-containing compounds that can be conveniently converted to 2,6-naphthyridine derivatives is reported.

Details

Language :
English
ISSN :
1523-7052
Volume :
17
Issue :
12
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
26068506
Full Text :
https://doi.org/10.1021/acs.orglett.5b01554