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Health-related quality of life and sleep among Chinese children after living donor liver transplantation.
- Source :
-
Pediatric transplantation [Pediatr Transplant] 2015 Aug; Vol. 19 (5), pp. 547-54. Date of Electronic Publication: 2015 Jun 11. - Publication Year :
- 2015
-
Abstract
- LDLT is a well-established treatment for most terminal liver diseases in children. Survival rates have improved, yet few studies have considered HRQoL or sleep problems in LDLT recipients. In this cross-sectional study, we enrolled 51 children who had undergone LDLT in Renji Hospital. PedsQL(™) 4.0 Generic Core Scales, PedsQL(™) 3.0 Transplant Module, and Pediatric Sleep Questionnaire were used to assess outcomes. Of all participants, 11.8% (6/51) reported low total HRQoL scores. Participants' scores on most HRQoL subscales were comparable to the scores of healthy children. However, compared with solid organ transplant recipients, LDLT recipients scored significantly lower in About My Medicines II (t = 3.092, p = 0.002) and Worry (t = 2.760, p = 0.006). Sleep problems (41.2%) were common among participants. Hierarchical regression analyses showed that SRBD accounted for significant variance in HRQoL on total generic HRQoL (R(2) = 0.446, p < 0.001), psychosocial health (R(2) = 0.372, p = 0.001), physical health (R(2) = 0.345, p = 0.003), total transplant-specific HRQoL (R(2) = 0.514, p < 0.001), About My Medicines I (R(2) = 0.365, p = 0.013), My Transplant and Others (R(2) = 0.334, p = 0.005), Pain and Hurt (R(2) = 0.544, p < 0.001), Worry (R(2) = 0.401, p = 0.001), Treatment Anxiety (R(2) = 0.526, p < 0.001), How I Look (R(2) = 0.221, p = 0.040), and Communication (R(2) = 0.343, p = 0.012). In conclusion, sleep problems are non-negligible in children after LDLT and predicted significant variance on HRQoL.<br /> (© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Subjects :
- Child
Child, Preschool
China
Cross-Sectional Studies
Female
Health Status
Humans
Liver Transplantation methods
Male
Psychometrics
Sleep Wake Disorders complications
Surveys and Questionnaires
Treatment Outcome
Liver Failure psychology
Liver Failure surgery
Liver Transplantation psychology
Living Donors
Quality of Life
Sleep
Subjects
Details
- Language :
- English
- ISSN :
- 1399-3046
- Volume :
- 19
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pediatric transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 26096790
- Full Text :
- https://doi.org/10.1111/petr.12532