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A new isoflavanone from the trunk of Horsfieldia pandurifolia.
- Source :
-
Natural product research [Nat Prod Res] 2016; Vol. 30 (2), pp. 131-7. Date of Electronic Publication: 2015 Jun 29. - Publication Year :
- 2016
-
Abstract
- A new isoflavanone, 2,2'-epoxy-4'-methoxy-3,7-dihydroxyisoflavanone (1), and a new natural coumaranone, 2-hyroxy-2-(4'-methoxybenzyl)-6-methoxy-3-coumaranone (2), along with 26 known compounds, were first isolated from the trunk of Horsfieldia pandurifolia. Their structures were elucidated by the means of spectroscopic analysis. Compound 1 was assessed for its cytotoxicity against five human tumour lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that it has no activity.
- Subjects :
- Benzyl Compounds chemistry
Benzyl Compounds isolation & purification
Benzyl Compounds pharmacology
Cell Line, Tumor drug effects
Coumarins chemistry
Coumarins isolation & purification
Coumarins pharmacology
Drug Screening Assays, Antitumor methods
HL-60 Cells drug effects
Humans
Isoflavones isolation & purification
Isoflavones pharmacology
Magnetic Resonance Spectroscopy
Molecular Structure
Spectrometry, Mass, Electrospray Ionization
Isoflavones chemistry
Myristicaceae chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 30
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 26119144
- Full Text :
- https://doi.org/10.1080/14786419.2015.1043554