Decarboxylative alkynylation and carbonylative alkynylation of carboxylic acids enabled by visible-light photoredox catalysis.

Authors :: Zhou QQ
Guo W
Ding W
Wu X
Chen X
Lu LQ
Xiao WJ
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Sep 14; Vol. 54 (38), pp. 11196-9. Date of Electronic Publication: 2015 Jul 06.
Publication Year :: 2015
Abstract: Visible-light-induced photocatalytic decarboxylative alkynylations of carboxylic acids have been developed for the first time. The reaction features extremely mild conditions, broad substrate scope, and avoids additional oxidants. Importantly, a decarboxylative carbonylative alkynylation has also been carried out in the presence of carbon monoxide (CO) under photocatalytic conditions, which affords valuable ynones in high yields at room temperature.<br /> (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Subjects :: Catalysis
Oxidation-Reduction
Alkynes chemistry
Carboxylic Acids chemistry
Light

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