Candidate biomarkers in heart failure with reduced and preserved ejection fraction.

Authors :: Sinning C
Zengin E
Zeller T
Schnabel RB
Blankenberg S
Westermann D
Source :: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2015; Vol. 20 (4), pp. 258-65.
Publication Year :: 2015
Abstract: Context: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.<br />Objective: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.<br />Methods: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.<br />Results: The results of 47 diseased and general population cohorts were included.<br />Conclusion: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.

Subjects :: Adrenomedullin analysis
Growth Differentiation Factor 15 analysis
Heart Failure diagnosis
Humans
Peptide Fragments analysis
Prognosis
Protein Precursors analysis
Sensitivity and Specificity
Biomarkers analysis
Heart Failure metabolism
Heart Failure physiopathology
Stroke Volume

Language :: English
ISSN :: 1366-5804
Volume :: 20
Issue :: 4
Database :: MEDLINE
Journal :: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Publication Type :: Academic Journal
Accession number :: 26301884
Full Text :: https://doi.org/10.3109/1354750X.2015.1068856

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