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Opening New Scenarios for Human MAO Inhibitors.
- Source :
-
Central nervous system agents in medicinal chemistry [Cent Nerv Syst Agents Med Chem] 2016; Vol. 16 (2), pp. 98-104. - Publication Year :
- 2016
-
Abstract
- Despite the considerable interest in the search of new and potent human MAO inhibitors, an increasing number of research works deal with new therapeutic and analytical approaches regarding these molecules. Our interest was focused on the detailed analysis of (i) new pharmacological options for selective hMAO inhibitors; (ii) innovative analytical procedures to discover/screen hMAO inhibitors, and (iii) the recent possibility of using labeled hMAO inhibitors to unravel neurodegenerative diseases and drug distribution. All these three aspects could open new scenarios stimulating the interest of researchers in this field.
- Subjects :
- Binding Sites
Humans
Monoamine Oxidase Inhibitors metabolism
Neurodegenerative Diseases diagnostic imaging
Neurodegenerative Diseases drug therapy
Neurodegenerative Diseases enzymology
Neuroimaging methods
Structure-Activity Relationship
Monoamine Oxidase metabolism
Monoamine Oxidase Inhibitors chemistry
Monoamine Oxidase Inhibitors therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1875-6166
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Central nervous system agents in medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 26320583
- Full Text :
- https://doi.org/10.2174/1871524915666150831141705