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Synthesis of functionalized tryptamines by Brønsted acid catalysed cascade reactions.

Authors :
Melis N
Secci F
Boddaert T
Aitken DJ
Frongia A
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Oct 25; Vol. 51 (83), pp. 15272-5. Date of Electronic Publication: 2015 Sep 03.
Publication Year :
2015

Abstract

An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction sequence.

Details

Language :
English
ISSN :
1364-548X
Volume :
51
Issue :
83
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
26335843
Full Text :
https://doi.org/10.1039/c5cc06855j