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Risk factors for surgical site infection and delayed wound healing after orthopedic surgery in rheumatoid arthritis patients.
- Source :
-
Modern rheumatology [Mod Rheumatol] 2016; Vol. 26 (1), pp. 68-74. Date of Electronic Publication: 2015 Sep 10. - Publication Year :
- 2016
-
Abstract
- Objective: To investigate the prevalence and the risk factors of surgical-site infection (SSI) and delayed wound healing (DWH) in patients with rheumatoid arthritis (RA) underwent orthopedic surgery.<br />Methods: We reviewed the records of 1036 elective orthopedic procedures undertaken in RA patients. Risk factors for SSI and DWH were assessed by logistic regression analysis using age, body mass index, disease duration, pre-operative laboratory data, surgical procedure, corticosteroid use, co-morbidity, and use of conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) and biological DMARDs (bDMARDs) as variables.<br />Results: SSI and DWH were identified in 19 cases and 15 cases, respectively. One case of SSI and three cases of DWH were recorded among 196 procedures in patients using bDMARDs. Foot and ankle surgery was associated with an increased risk of SSI (odds ratio (OR), 3.167; 95% confidence interval (CI), 1.256-7.986; p = 0.015). Total knee arthroplasty (TKA; OR, 4.044; 95% CI, 1.436-11.389; p = 0.008) and disease duration (OR, 1.004; 95% CI, 1.000-1.007; p = 0.029) were associated with an increased risk of DWH.<br />Conclusions: Our results indicated foot and ankle surgery, and TKA and disease duration as risk factors for SSI and DWH, respectively. bDMARDs was not associated with an increased risk of SSI and DWH.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Antirheumatic Agents therapeutic use
Arthritis, Rheumatoid drug therapy
Arthroplasty, Replacement, Knee adverse effects
Female
Humans
Male
Middle Aged
Risk Factors
Treatment Outcome
Young Adult
Arthritis, Rheumatoid surgery
Orthopedic Procedures adverse effects
Surgical Wound Infection etiology
Wound Healing physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1439-7609
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Modern rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 26357931
- Full Text :
- https://doi.org/10.3109/14397595.2015.1073133