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Herpes simplex virus 2 hepatitis in a lung transplant recipient: a diagnostic challenge.

Authors :
Hirschi S
Biondini D
Ohana M
Solis M
D'Urso A
Rosner V
Kessler R
Source :
Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2015 Dec; Vol. 17 (6), pp. 904-8. Date of Electronic Publication: 2015 Nov 05.
Publication Year :
2015

Abstract

Herpes simplex virus (HSV) hepatitis is a rare and serious complication in immunocompromised patients. We report the case of an HSV hepatitis occurring 4 years after lung transplantation in a cystic fibrosis patient. The presentation was nonspecific, mimicking acute cholecystitis; orogenital signs were absent. The diagnosis was made based on viral cultures performed during cholecystectomy and confirmed by blood quantitative polymerase chain reaction. Although the diagnosis and treatment were delayed, the patient fully recovered with acyclovir, reduced immunosuppression, and intravenous immunoglobulins. The diagnostic difficulties, prognostic factors, and treatments of this infection are discussed.<br /> (© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1399-3062
Volume :
17
Issue :
6
Database :
MEDLINE
Journal :
Transplant infectious disease : an official journal of the Transplantation Society
Publication Type :
Academic Journal
Accession number :
26370068
Full Text :
https://doi.org/10.1111/tid.12459