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[Treatment of Epidermal Growth Factor Receptor Inhibitors Associated Adverse Skin Reactions by Zhiyang Pingfu Liquid: a Clinical Study].
- Source :
-
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine [Zhongguo Zhong Xi Yi Jie He Za Zhi] 2015 Jul; Vol. 35 (7), pp. 820-2. - Publication Year :
- 2015
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Abstract
- Objective: To study the curative effect of Zhiyang Pingfu Liquid (ZPL) in treating epidermal growth factor receptor inhibitors (EGFRIs) associated adverse reactions of the skin.<br />Methods: All 54 patients with pathologically confirmed malignant tumor had EGFRIs induced adverse reactions of the skin to various degrees. ZPL was externally applied for them all, once or twice per day, 14 days consisting of one therapeutic course. Changes of adverse skin reactions, time for symptoms relief, adverse skin reaction types suitable for ZPL were observed before and after treatment.<br />Results: EGFRIs associated skin adverse reactions were improved to various degrees after they used ZPL. The shortest symptoms relief time was 1 day while the longest was 12 days, with an average of 6.93 days and the median time 7 days. Compared with before treatment, itching, rash/scaling, acne/acneform eruptions were obviously improved (P < 0.05).<br />Conclusion: ZPL could alleviate EGFRls associated adverse skin reactions, especially showed better effect on itching, rash/scaling, acne/acneform eruptions.
- Subjects :
- Biomedical Research
Drugs, Chinese Herbal administration & dosage
Exanthema chemically induced
Humans
Neoplasms drug therapy
Pruritus
Skin drug effects
Antineoplastic Agents adverse effects
Drugs, Chinese Herbal therapeutic use
ErbB Receptors antagonists & inhibitors
Skin Diseases drug therapy
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1003-5370
- Volume :
- 35
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
- Publication Type :
- Academic Journal
- Accession number :
- 26380445