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The Use of Interferons in the Treatment of Cutaneous T-Cell Lymphoma.

Authors :
Spaccarelli N
Rook AH
Source :
Dermatologic clinics [Dermatol Clin] 2015 Oct; Vol. 33 (4), pp. 731-45. Date of Electronic Publication: 2015 Aug 20.
Publication Year :
2015

Abstract

Interferons are polypeptides that naturally occur in the human body as a part of the innate immune response. By harnessing these immunomodulatory functions, synthetic interferons have shown efficacy in combating various diseases including cutaneous T-cell lymphoma. This article closely examines the qualities of interferon alfa and interferon gamma and the evidence behind their use in the 2 most common types of cutaneous T-cell lymphomas, namely, mycosis fungoides and Sézary syndrome.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-0520
Volume :
33
Issue :
4
Database :
MEDLINE
Journal :
Dermatologic clinics
Publication Type :
Academic Journal
Accession number :
26433845
Full Text :
https://doi.org/10.1016/j.det.2015.05.008