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Injectable 2D MoS2 -Integrated Drug Delivering Implant for Highly Efficient NIR-Triggered Synergistic Tumor Hyperthermia.

Authors :
Wang S
Chen Y
Li X
Gao W
Zhang L
Liu J
Zheng Y
Chen H
Shi J
Source :
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2015 Nov 25; Vol. 27 (44), pp. 7117-22. Date of Electronic Publication: 2015 Oct 08.
Publication Year :
2015

Abstract

MoS2 nanosheets and a doxorubicin (DOX)-containing poly (lactic-co-glycolic acid) (PLGA)/MoS2 /DOX composite implant are successfully constructed based on the unique phase-changing behavior of PLGA/MoS2 /DOX oleosol within tumors. The fast phase transformation can firmly restrict MoS2 and DOX within tumors, and the integrated MoS2 and DOX can endow the implant with high synergistic photothermal and chemotherapeutic efficiency against tumors.<br /> (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-4095
Volume :
27
Issue :
44
Database :
MEDLINE
Journal :
Advanced materials (Deerfield Beach, Fla.)
Publication Type :
Academic Journal
Accession number :
26447460
Full Text :
https://doi.org/10.1002/adma.201503869