Anti-Mycobacterium tuberculosis activity of antituberculosis drugs and amoxicillin/clavulanate combination.

Authors :: Pagliotto AD
Caleffi-Ferracioli KR
Lopes MA
Baldin VP
Leite CQ
Pavan FR
Scodro RB
Siqueira VL
Cardoso RF
Source :: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2016 Dec; Vol. 49 (6), pp. 980-983. Date of Electronic Publication: 2015 Sep 21.
Publication Year :: 2016
Abstract: We report the in vitro drugs interaction by the resazurin drugs combination microtiter assay (REDCA) of amoxicillin (AMO)/clavulanate (CLAV) with isoniazid (INH), ethambutol (EMB), and rifampicin (RIF) against susceptible and resistant Mycobacterium tuberculosis isolates. The addition of AMO/CLAV to classical antituberculosis drugs should be explored as a promising alternative for the treatment of resistant tuberculosis (TB).<br /> (Copyright © 2015. Published by Elsevier B.V.)

Subjects :: Drug Resistance, Multiple, Bacterial
Humans
Microbial Sensitivity Tests
Mycobacterium tuberculosis isolation & purification
Oxazines analysis
Xanthenes analysis
Amoxicillin pharmacology
Antitubercular Agents pharmacology
Clavulanic Acid pharmacology
Ethambutol pharmacology
Isoniazid pharmacology
Mycobacterium tuberculosis drug effects
Rifampin pharmacology

Language :: English
ISSN :: 1995-9133
Volume :: 49
Issue :: 6
Database :: MEDLINE
Journal :: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Publication Type :: Academic Journal
Accession number :: 26454420
Full Text :: https://doi.org/10.1016/j.jmii.2015.08.025

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