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Improved Transversal Relaxivity for Highly Crystalline Nanoparticles of Pure γ-Fe2O3 Phase.
Improved Transversal Relaxivity for Highly Crystalline Nanoparticles of Pure γ-Fe2O3 Phase.
- Source :
-
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2015 Dec 14; Vol. 21 (51), pp. 18855-61. Date of Electronic Publication: 2015 Nov 06. - Publication Year :
- 2015
-
Abstract
- Pure and highly crystalline γ-Fe2O3 nanocrystals (NCs) are obtained when hydrolysis and oxidation of a Fe(II) organometallic precursor are performed in successive steps. Their synthesis in pure alkylamine leads to NCs of about 6 nm. In aqueous solutions of poly(vinyl)pyrrolidone, such pristine NCs form aggregates of about 150 nm that exhibit a high transversal relaxivity (r2 =466 mM(-1) s(-1)) about four times higher than that of a commercial Feridex magnetic resonance imaging (MRI) contrast agent. Consequently, they provide a significant decrease in the NMR signal at very short echo time (8 ms), which is of paramount importance in clinical practice because of the reduced duration of MRI measurements.<br /> (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Details
- Language :
- English
- ISSN :
- 1521-3765
- Volume :
- 21
- Issue :
- 51
- Database :
- MEDLINE
- Journal :
- Chemistry (Weinheim an der Bergstrasse, Germany)
- Publication Type :
- Academic Journal
- Accession number :
- 26542051
- Full Text :
- https://doi.org/10.1002/chem.201502905