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[Treatment of non-cirrhotic, non-tumoural portal vein thrombosis].

Authors :
Llop E
Seijo S
Source :
Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2016 Jun-Jul; Vol. 39 (6), pp. 403-10. Date of Electronic Publication: 2015 Nov 04.
Publication Year :
2016

Abstract

Thrombosis of the splenoportal axis not associated with liver cirrhosis or neoplasms is a rare disease whose prevalence ranges from 0.7 to 3.7 per 100,000 inhabitants. However, this entity is the second most common cause of portal hypertension. Prothrombotic factors are present as an underlying cause in up to 70% of patients and local factors in 10-50%. The coexistence of several etiological factors is frequent. Clinical presentation may be acute or chronic (portal cavernomatosis). The acute phase can present as abdominal pain, nausea, vomiting, fever, rectorrhagia, intestinal congestion, and ischemia. In this phase, early initiation of anticoagulation is essential to achieve portal vein recanalization and thus improve patient prognosis. In the chronic phase, symptoms are due to portal hypertension syndrome. In this phase, the aim of treatment is to treat or prevent the complications of portal hypertension. Anticoagulation is reserved to patients with a proven underlying thrombophilic factor.<br /> (Copyright © 2016 Elsevier España, S.L.U. y AEEH y AEG. All rights reserved.)

Details

Language :
Spanish; Castilian
ISSN :
0210-5705
Volume :
39
Issue :
6
Database :
MEDLINE
Journal :
Gastroenterologia y hepatologia
Publication Type :
Academic Journal
Accession number :
26547613
Full Text :
https://doi.org/10.1016/j.gastrohep.2015.09.007