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The enteric microbiome in hepatobiliary health and disease.

Authors :
Tabibian JH
Varghese C
LaRusso NF
O'Hara SP
Source :
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2016 Apr; Vol. 36 (4), pp. 480-7. Date of Electronic Publication: 2015 Dec 12.
Publication Year :
2016

Abstract

Increasing evidence points to the contribution of the intestinal microbiome as a potentially key determinant in the initiation and/or progression of hepatobiliary disease. While current understanding of this dynamic is incomplete, exciting insights are continually being made and more are expected given the developments in molecular and high-throughput omics techniques. In this brief review, we provide a practical and updated synopsis of the interaction of the intestinal microbiome with the liver and its downstream impact on the initiation, progression and complications of hepatobiliary disease.<br /> (© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1478-3231
Volume :
36
Issue :
4
Database :
MEDLINE
Journal :
Liver international : official journal of the International Association for the Study of the Liver
Publication Type :
Academic Journal
Accession number :
26561779
Full Text :
https://doi.org/10.1111/liv.13009