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The First Case of Invasive Mixed-Mold Infections Due to Emericella nidulans var. echinulata and Rasamsonia piperina in a Patient with Chronic Granulomatous Disease.
- Source :
-
Mycopathologia [Mycopathologia] 2016 Apr; Vol. 181 (3-4), pp. 305-9. Date of Electronic Publication: 2015 Nov 13. - Publication Year :
- 2016
-
Abstract
- A 16-year-old boy with chronic granulomatous disease presented with pneumonia and rib osteomyelitis. Emericella nidulans var. echinulata was isolated from his sputum. After starting voriconazole, Rasamsonia piperina was isolated from the rib swelling. A combination therapy of voriconazole and micafungin effectively eradicated this invasive mixed-mold infection. In immunocompromised patients, a precise pathogenic diagnosis is clinically useful for administration of an appropriate treatment regimen.
- Subjects :
- Adolescent
Ascomycota isolation & purification
Coinfection drug therapy
Emericella isolation & purification
Humans
Immunocompromised Host
Male
Micafungin
Sputum microbiology
Antifungal Agents therapeutic use
Ascomycota drug effects
Echinocandins therapeutic use
Emericella drug effects
Granulomatous Disease, Chronic microbiology
Lipopeptides therapeutic use
Mycoses drug therapy
Mycoses microbiology
Voriconazole therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1573-0832
- Volume :
- 181
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- Mycopathologia
- Publication Type :
- Academic Journal
- Accession number :
- 26563166
- Full Text :
- https://doi.org/10.1007/s11046-015-9963-5