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Procedural sedation during transradial coronary angiography to prevent spasm.
- Source :
-
Herz [Herz] 2016 Aug; Vol. 41 (5), pp. 435-8. Date of Electronic Publication: 2015 Nov 23. - Publication Year :
- 2016
-
Abstract
- Aim: Radial artery spasm is common during transradial procedures and is the most common cause of procedural failure. The objectives of this study were to assess whether the routine administration of sedation at the beginning of transradial coronary angiography with the use of hydrophilic-coated and smaller sheaths/catheters would reduce the incidence of radial artery spasm.<br />Patients and Methods: Patients undergoing transradial coronary angiography were prospectively randomized to receive midazolam during the procedure or no sedative treatment. The primary endpoint was angiographically confirmed radial artery spasm. Stenosis of the radial artery was measured with a computer-assisted quantification method.<br />Results: In all, 150 patients were randomized into a treatment group and a control group. Spasm occurred in 15 patients of the treatment group (20 %) versus 16 in the control group (21.3 %). There were no differences between the two groups regarding the incidence of spasm and the distribution of spasm severity (p > 0.05). No significant differences were observed between the two groups in terms of 30-day mortality or repeat hospitalization for any cause (p > 0.05).<br />Conclusion: Routine use of midazolam could not reduce the occurrence of radial artery spasm during transradial coronary angiography.
- Subjects :
- Catheterization, Peripheral methods
Coronary Angiography methods
Coronary Artery Disease therapy
Humans
Hypnotics and Sedatives administration & dosage
Male
Midazolam administration & dosage
Middle Aged
Radiographic Image Enhancement methods
Reproducibility of Results
Sensitivity and Specificity
Spasm etiology
Treatment Outcome
Catheterization, Peripheral adverse effects
Conscious Sedation methods
Coronary Angiography adverse effects
Coronary Artery Disease diagnostic imaging
Radial Artery drug effects
Spasm prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1615-6692
- Volume :
- 41
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Herz
- Publication Type :
- Academic Journal
- Accession number :
- 26598418
- Full Text :
- https://doi.org/10.1007/s00059-015-4373-5