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Ibrutinib and idelalisib target B cell receptor- but not CXCL12/CXCR4-controlled integrin-mediated adhesion in Waldenström macroglobulinemia.
- Source :
-
Haematologica [Haematologica] 2016 Mar; Vol. 101 (3), pp. e111-5. Date of Electronic Publication: 2015 Dec 03. - Publication Year :
- 2016
- Subjects :
- Adenine analogs & derivatives
Agammaglobulinaemia Tyrosine Kinase
Cell Adhesion drug effects
Cell Line, Tumor
Cell Proliferation drug effects
Cell Survival drug effects
Chemokine CXCL12 genetics
Chemokine CXCL12 immunology
Humans
Integrin alpha4beta1 genetics
Integrin alpha4beta1 immunology
Molecular Targeted Therapy
Myeloid Differentiation Factor 88 genetics
Myeloid Differentiation Factor 88 immunology
Piperidines
Plasma Cells immunology
Plasma Cells pathology
Protein-Tyrosine Kinases genetics
Protein-Tyrosine Kinases immunology
Receptors, Antigen, B-Cell antagonists & inhibitors
Receptors, Antigen, B-Cell immunology
Receptors, CXCR4 genetics
Receptors, CXCR4 immunology
Signal Transduction
Vascular Cell Adhesion Molecule-1 genetics
Vascular Cell Adhesion Molecule-1 immunology
Waldenstrom Macroglobulinemia genetics
Waldenstrom Macroglobulinemia immunology
Waldenstrom Macroglobulinemia pathology
Antineoplastic Agents pharmacology
Gene Expression Regulation, Neoplastic
Plasma Cells drug effects
Purines pharmacology
Pyrazoles pharmacology
Pyrimidines pharmacology
Quinazolinones pharmacology
Receptors, Antigen, B-Cell genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1592-8721
- Volume :
- 101
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Haematologica
- Publication Type :
- Report
- Accession number :
- 26635033
- Full Text :
- https://doi.org/10.3324/haematol.2015.137265