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The Rotterdam Scan Study: design update 2016 and main findings.
- Source :
-
European journal of epidemiology [Eur J Epidemiol] 2015 Dec; Vol. 30 (12), pp. 1299-315. Date of Electronic Publication: 2015 Dec 09. - Publication Year :
- 2015
-
Abstract
- Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study.
- Subjects :
- Aged
Aged, 80 and over
Brain blood supply
Brain Mapping
Cerebral Arteries physiopathology
Chronic Disease
Female
Humans
Image Interpretation, Computer-Assisted
Image Processing, Computer-Assisted
Longitudinal Studies
Male
Middle Aged
Nervous System Diseases pathology
Netherlands
Neuroimaging
Prospective Studies
Risk Factors
Aging pathology
Brain pathology
Cerebral Arteries pathology
Magnetic Resonance Imaging methods
Nervous System Diseases etiology
Population Surveillance methods
Subjects
Details
- Language :
- English
- ISSN :
- 1573-7284
- Volume :
- 30
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- European journal of epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 26650042
- Full Text :
- https://doi.org/10.1007/s10654-015-0105-7