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The Rotterdam Scan Study: design update 2016 and main findings.

Authors :
Ikram MA
van der Lugt A
Niessen WJ
Koudstaal PJ
Krestin GP
Hofman A
Bos D
Vernooij MW
Source :
European journal of epidemiology [Eur J Epidemiol] 2015 Dec; Vol. 30 (12), pp. 1299-315. Date of Electronic Publication: 2015 Dec 09.
Publication Year :
2015

Abstract

Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study.

Details

Language :
English
ISSN :
1573-7284
Volume :
30
Issue :
12
Database :
MEDLINE
Journal :
European journal of epidemiology
Publication Type :
Academic Journal
Accession number :
26650042
Full Text :
https://doi.org/10.1007/s10654-015-0105-7