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Occupation and risk of sudden death in a United States community: a case-control analysis.
- Source :
-
BMJ open [BMJ Open] 2015 Dec 18; Vol. 5 (12), pp. e009413. Date of Electronic Publication: 2015 Dec 18. - Publication Year :
- 2015
-
Abstract
- Objective: Work environment is said to influence cardiovascular risk. We assessed whether nature of occupation affects risk of sudden cardiac death (SCD) in the general population.<br />Methods: In the ongoing, prospective Oregon Sudden Unexpected Death Study (catchment population 1 million), working-age SCD cases (18-65 years) were compared with controls who died from any cause. Usual occupation obtained from death certificates was classified using the US Census Bureau standard occupational classification descriptions and categorised as white collar, blue collar or homemaker. Odds ratio (OR) for SCD by occupation category was obtained and clinical profile of SCD cases was compared by occupation type.<br />Results: Among SCD cases (n=646; 74% male) compared to controls (n=622; 73.6% male), the proportion of white collar workers was higher among male SCD cases (52.7% vs 43.7%; p=0.01); the difference in females was smaller (59.5% vs 55%; p=0.62). Adjusting for race and smoking status, male white collar workers had a higher risk of SCD compared to blue collar workers (OR=1.67, (1.26 to 2.23), p<0.001). A similar, non-significant trend was observed among females (OR 1.49 (0.81 to 2.75); p=0.20). White collar SCD cases were less likely to be current smokers (34.7% vs 45.3%, p=0.008), drug misusers (13.1% vs 18.5%) or have diabetes (21.4% vs 28.2%, both p=0.07) compared to blue collar workers. Other cardiac risk factors were similar.<br />Conclusions: A white collar occupation was associated with increased risk of SCD, when compared to blue collar occupations. Since differences in conventional risk factors did not explain this elevated risk, work-related behavioural and psychosocial stressors warrant a closer evaluation.<br /> (Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/)
- Subjects :
- Adult
Case-Control Studies
Diabetes Mellitus epidemiology
Female
Humans
Male
Middle Aged
Odds Ratio
Oregon epidemiology
Prospective Studies
Risk Factors
Smoking epidemiology
Stress, Psychological
Substance-Related Disorders epidemiology
Death, Sudden, Cardiac etiology
Occupations classification
Residence Characteristics
Work
Subjects
Details
- Language :
- English
- ISSN :
- 2044-6055
- Volume :
- 5
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- BMJ open
- Publication Type :
- Academic Journal
- Accession number :
- 26685031
- Full Text :
- https://doi.org/10.1136/bmjopen-2015-009413