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[Transdermal Delivery of NSAIDs].

Authors :
Nakajima T
Makino K
Source :
Masui. The Japanese journal of anesthesiology [Masui] 2015 Nov; Vol. 64 (11), pp. 1141-4.
Publication Year :
2015

Abstract

Skin has been studied as administration site of drug for its systemic effects, since systemic therapeutic agents can be delivered for long time with a controlled ratio, escaping from the first pass effect by liver by the transdermal delivery, which can decrease the dosage form. The low permeability of drug molecules through stratum corneum has been the limiting factor for developing transdermal delivery system of therapeutic agents. To enhance the permeability of drug molecules, many studies have been reported.

Details

Language :
Japanese
ISSN :
0021-4892
Volume :
64
Issue :
11
Database :
MEDLINE
Journal :
Masui. The Japanese journal of anesthesiology
Publication Type :
Academic Journal
Accession number :
26689064