Treatment Outcomes of Childhood TB in Lagos, Nigeria.

Authors :: Adejumo OA
Daniel OJ
Adebayo BI
Adejumo EN
Jaiyesimi EO
Akang G
Awe A
Source :: Journal of tropical pediatrics [J Trop Pediatr] 2016 Apr; Vol. 62 (2), pp. 131-8. Date of Electronic Publication: 2015 Dec 24.
Publication Year :: 2016
Abstract: Background: : Treatment outcomes of tuberculosis (TB) in children are rarely evaluated by most national TB programmes in sub-Saharan Africa. This study evaluated the treatment outcomes of children treated for TB in Lagos State, Nigeria.<br />Methods: A retrospective review of programme data of the Lagos state TB and the Leprosy control programme in Nigeria from 1 January 2012 to 31 December 2012. Treatment outcomes were categorized according to the national TB guidelines.<br />Results: A total of 535 cases of childhood TB were notified in 2012, representing 6.3% of the total TB cases notified in Lagos state in 2012. The prevalence of TB/HIV co-infection was 29%. The treatment success rate was 79.2% in TB/HIV-negative children compared with 73.4% in TB/HIV-positive children (p = 0.1268). Children <1 year had the worst treatment outcomes (p < 0.001).<br />Conclusion: There is a need to intensify effort at improving notification and treatment outcomes in children.<br /> (© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)