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[A Case of Gastrointestinal Perforation in a Patient with Colon Cancer and Stent Placement during Bevacizumab Treatment, Alleviated with Conservative Therapy].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2015 Nov; Vol. 42 (12), pp. 2148-50. - Publication Year :
- 2015
-
Abstract
- The case involved a 52-year-old man. He was diagnosed with sigmoid colon cancer and multiple liver and lung metastases. After placement of a metallic stent for circumferential stricture, 5-fluorouracil/Leucovorin/oxaliplatin (FOLFOX4) plus bevacizumab therapy was introduced. After 17 courses, gastrointestinal perforation was noted at the site of stent placement, but this was alleviated with conservative therapy. Although gastrointestinal perforation is known to be a serious complication that occurs during chemotherapy combined with bevacizumab, further studies are needed to investigate the incidence of gastrointestinal perforation after stent placement more fully.
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols therapeutic use
Bevacizumab therapeutic use
Humans
Liver Neoplasms drug therapy
Liver Neoplasms secondary
Lung Neoplasms drug therapy
Lung Neoplasms secondary
Male
Middle Aged
Sigmoid Neoplasms pathology
Bevacizumab adverse effects
Intestinal Perforation etiology
Sigmoid Neoplasms therapy
Stents
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 42
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 26805293