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Prevalence of salivary Epstein-Barr virus in potentially malignant oral disorders and oral squamous cell carcinoma.
- Source :
-
Medicina oral, patologia oral y cirugia bucal [Med Oral Patol Oral Cir Bucal] 2016 Mar 01; Vol. 21 (2), pp. e157-60. Date of Electronic Publication: 2016 Mar 01. - Publication Year :
- 2016
-
Abstract
- Background: To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders.<br />Material and Methods: Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR.<br />Results: The highest percentage of positive salivary EBV DNA corresponded to the OSCC group (58.3%), followed by the PMD group (41.7%) and the controls (40.4%). The differences between groups were not statistically significant, however (p>0.05).<br />Conclusions: Salivary EBV DNA was more prevalent in OSCC than in PMD or the controls.
Details
- Language :
- English
- ISSN :
- 1698-6946
- Volume :
- 21
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Medicina oral, patologia oral y cirugia bucal
- Publication Type :
- Academic Journal
- Accession number :
- 26827058
- Full Text :
- https://doi.org/10.4317/medoral.20785