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The Value of T-SPOT.TB in Early Diagnosis of Tracheobronchial Tuberculosis.
- Source :
-
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [Sarcoidosis Vasc Diffuse Lung Dis] 2016 Jan 18; Vol. 32 (4), pp. 336-41. Date of Electronic Publication: 2016 Jan 18. - Publication Year :
- 2016
-
Abstract
- Objective: To evaluate the value of T-SPOT.TB in the diagnosis of tracheobronchial tuberculosis.<br />Methods: This study included in January 2010 to October 2014 in the three gorges university during the first clinical medical college of final 283 diagnosed with tracheal bronchus TB patients (including 273 patients with pathological biopsy diagnosis and 10 called suspected TB patients), at the same time will be 283 active TB patients as a parallel control group included in this study. They were all given traditional detection methods acid fast stain and diseased tissue pathological biopsy and the new detection method T-SPOT.TB.<br />Results: Sputum smear acid-fast stain sensitivity rate is 39.2% (111/283), typical TB diseased tissue pathology biopsy pathology morphology of 221 cases (78.1%), tend to TB 52 cases (18.4%),while T-SPOT. TB testing sensitivity and speciality rate is 93.6% (265/283) and 85.1% (241/283), which is much higher then the former two.<br />Conclusion: T-SPOT.TB can provide important basis for the diagnosis of tracheobronchial tuberculosis.It is the fastest and most accu-rate method in the diagnosis of tracheobronchial tuberculosis.
- Subjects :
- Adolescent
Adult
Biomarkers metabolism
Bronchial Diseases immunology
Bronchial Diseases microbiology
China
Female
Humans
Interferon-gamma metabolism
Male
Middle Aged
Mycobacterium tuberculosis isolation & purification
Predictive Value of Tests
Reproducibility of Results
Sputum microbiology
T-Lymphocytes immunology
Tracheal Diseases immunology
Tracheal Diseases microbiology
Tuberculosis, Pulmonary immunology
Tuberculosis, Pulmonary microbiology
Young Adult
Bronchial Diseases diagnosis
Enzyme-Linked Immunospot Assay
Interferon-gamma Release Tests
Mycobacterium tuberculosis immunology
T-Lymphocytes microbiology
Tracheal Diseases diagnosis
Tuberculosis, Pulmonary diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 2532-179X
- Volume :
- 32
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
- Publication Type :
- Academic Journal
- Accession number :
- 26847101