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Auxiliary partial liver transplantation for acute liver failure using "high risk" grafts: Case report.
- Source :
-
World journal of gastroenterology [World J Gastroenterol] 2016 Feb 07; Vol. 22 (5), pp. 1919-24. - Publication Year :
- 2016
-
Abstract
- Acute liver failure (ALF) is a reversible disorder that is associated with an abrupt loss of hepatic mass, rapidly progressive encephalopathy and devastating complications. Despite its high mortality, an emergency liver transplantation nowadays forms an integral part in ALF management and has substantially improved the outcomes of ALF. Here, we report the case of a 32-year-old female patient who was admitted with grade IV hepatic encephalopathy (coma) following drug-induced ALF. We performed an emergency auxiliary partial orthotopic liver transplantation with a "high risk" graft (liver macrovesicular steatosis approximately 40%) from a living donor. The patient was discharged on postoperative day 57 with normal liver function. Weaning from immunosuppression was achieved 9 mo after transplantation. A follow-up using CT scan showed a remarkable increase in native liver volume and gradual loss of the graft. More than 6 years after the transplantation, the female now has a 4-year-old child and has returned to work full-time without any neurological sequelae.
- Subjects :
- Adult
Biopsy
Chemical and Drug Induced Liver Injury diagnosis
Chemical and Drug Induced Liver Injury etiology
Fatty Liver complications
Fatty Liver diagnosis
Female
Graft Survival
Humans
Immunosuppressive Agents administration & dosage
Liver Failure, Acute chemically induced
Liver Failure, Acute diagnosis
Liver Function Tests
Liver Transplantation adverse effects
Risk Factors
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Chemical and Drug Induced Liver Injury surgery
Donor Selection
Liver Failure, Acute surgery
Liver Regeneration
Liver Transplantation methods
Living Donors
Subjects
Details
- Language :
- English
- ISSN :
- 2219-2840
- Volume :
- 22
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- World journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 26855552
- Full Text :
- https://doi.org/10.3748/wjg.v22.i5.1919