Back to Search Start Over

An Enantioselective Assembly of Dihydropyranones through an NHC/LiCl-Mediated in situ Activation of α,β-Unsaturated Carboxylic Acids.

Authors :
Que Y
Lu Y
Wang W
Wang Y
Wang H
Yu C
Li T
Wang XS
Shen S
Yao C
Source :
Chemistry, an Asian journal [Chem Asian J] 2016 Mar 04; Vol. 11 (5), pp. 678-81. Date of Electronic Publication: 2016 Feb 10.
Publication Year :
2016

Abstract

A straightforward N-heterocyclic carbene (NHC)/LiCl-mediated synthesis of dihydropyranones from α,β-unsaturated carboxylic acids and 1,3-dicarbonyl compounds was realized through the in situ activation strategy. The key advantages of this protocol include ready availability and high stability of starting materials, good yields, and excellent enantioselectivity.<br /> (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1861-471X
Volume :
11
Issue :
5
Database :
MEDLINE
Journal :
Chemistry, an Asian journal
Publication Type :
Academic Journal
Accession number :
26864639
Full Text :
https://doi.org/10.1002/asia.201501353