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Novel Candidate Biomarkers of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma: A Systematic Review.
- Source :
-
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes [Eur Surg Res] 2016; Vol. 56 (3-4), pp. 141-53. Date of Electronic Publication: 2016 Feb 12. - Publication Year :
- 2016
-
Abstract
- There is no doubt that, along with surgery, chemoradiotherapy is an important treatment for esophageal squamous cell carcinoma (ESCC). Patients who respond well to chemoradiotherapy obtain great benefits toward overcoming their cancer, and so a more favorable prognosis. On the other hand, patients who do not respond well have wasted valuable time and experienced severe toxicity and seriously diminished quality of life, only to have their cancer recur with an unfavorable prognosis. For this reason, a reliable biomarker of chemoradiosensitivity in ESCC has long been sought. In this review, we will enumerate recently reported candidate biomarkers of chemoradiosensitivity in ESCC that have the potential for future clinical application.<br /> (© 2016 S. Karger AG, Basel.)
- Subjects :
- Esophageal Squamous Cell Carcinoma
Humans
Ki-67 Antigen analysis
Lithostathine analysis
NF-E2-Related Factor 2 analysis
Receptors, Interleukin-6 blood
Vascular Endothelial Growth Factor A blood
Vascular Endothelial Growth Factor A genetics
Biomarkers, Tumor analysis
Carcinoma, Squamous Cell therapy
Chemoradiotherapy
Esophageal Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9921
- Volume :
- 56
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes
- Publication Type :
- Academic Journal
- Accession number :
- 26867151
- Full Text :
- https://doi.org/10.1159/000443607