Prognostic value of three pro-nuclei (3PN) incidence in elective single blastocyst-stage embryo transfer.

Authors :: Li M
Zhao W
Li W
Zhao X
Shi J
Source :: International journal of clinical and experimental medicine [Int J Clin Exp Med] 2015 Nov 15; Vol. 8 (11), pp. 21699-702. Date of Electronic Publication: 2015 Nov 15 (Print Publication: 2015).
Publication Year :: 2015
Abstract: Objectives: To investigate whether 3PN incidence could lead to a worse pregnancy outcome of elective single blastocyst stage embryo transfer (eSBET).<br />Methods: This study included 706 eSBET cycles from January 2013 to March 2015. The patients were divided into two groups as follows: group 1 included 286 patients with no 3PN zygotes and group 2 included 420 patients with 3PN zygotes.<br />Main Outcome Measure: female age, endometrial thickness, infertility duration, type of infertility, main etiology of infertility, clinical pregnancy and abortion rate.<br />Results: We observed that there was no significant difference in female age, endometrial thickness, infertility duration and abortion rate between two groups. It's worth noting that the clinical pregnancy rate in 3PN > 0% group was significantly lower than 3PN = 0 group (P = 0.021).<br />Conclusions: 3PN incidence might make anegative effect on pregnancy outcomes in elective single blastocyst stage embryo transfer.

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