Allergen immunotherapy for insect venom allergy: protocol for a systematic review.

Authors :: Dhami S
Nurmatov U
Varga EM
Sturm G
Muraro A
Akdis CA
Antolín-Amérigo D
Bilò MB
Bokanovic D
Calderon MA
Cichocka-Jarosz E
Elberink JN
Gawlik R
Jakob T
Kosnik M
Lange J
Mingomataj E
Mitsias DI
Mosbech H
Pfaar O
Pitsios C
Pravettoni V
Roberts G
Ruëff F
Sin BA
Sheikh A
Source :: Clinical and translational allergy [Clin Transl Allergy] 2016 Feb 16; Vol. 6, pp. 6. Date of Electronic Publication: 2016 Feb 16 (Print Publication: 2015).
Publication Year :: 2016
Abstract: Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy.<br />Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.<br />Discussion: The findings from this review will be used to inform the development of recomendations for EAACI's Guidelines on AIT.

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