Back to Search
Start Over
Alkyne Difunctionalization by Dual Gold/Photoredox Catalysis.
- Source :
-
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Apr 18; Vol. 22 (17), pp. 5909-13. Date of Electronic Publication: 2016 Mar 08. - Publication Year :
- 2016
-
Abstract
- Highly selective tandem nucleophilic addition/cross-coupling reactions of alkynes have been developed using visible-light-promoted dual gold/photoredox catalysis. The simultaneous oxidation of Au(I) and coordination of the coupling partner by photo-generated aryl radicals, and the use of catalytically inactive gold precatalysts allows for high levels of selectivity for the cross-coupled products without competing hydrofunctionalization or homocoupling. As demonstrated in representative arylative Meyer-Schuster and hydration reactions, this work expands the scope of dual gold/photoredox catalysis to the largest class of substrates for gold catalysts and benefits from the mild and environmentally attractive nature of visible-light activation.<br /> (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Details
- Language :
- English
- ISSN :
- 1521-3765
- Volume :
- 22
- Issue :
- 17
- Database :
- MEDLINE
- Journal :
- Chemistry (Weinheim an der Bergstrasse, Germany)
- Publication Type :
- Academic Journal
- Accession number :
- 26888456
- Full Text :
- https://doi.org/10.1002/chem.201600710