DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation.

Authors :: Dhakal B
D'Souza A
Pasquini M
Saber W
Fenske TS
Moss RB
Drobyski WR
Hari P
Abidi MZ
Source :: Case reports in medicine [Case Rep Med] 2016; Vol. 2016, pp. 8503275. Date of Electronic Publication: 2016 Jan 28.
Publication Year :: 2016
Abstract: Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure.

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