Back to Search
Start Over
Epidemiology and Characteristics of Kikuchi-Fujimoto Disease in the African-Descent Population of Martinique, French West Indies.
- Source :
-
Arthritis care & research [Arthritis Care Res (Hoboken)] 2016 Dec; Vol. 68 (12), pp. 1883-1887. Date of Electronic Publication: 2016 Oct 21. - Publication Year :
- 2016
-
Abstract
- Objective: To provide an epidemiologic description of Kikuchi-Fujimoto disease (KFD), and to describe its relationship with systemic lupus erythematosus (SLE) in a population of sub-Saharan origin.<br />Methods: Patients were retrospectively included on the basis of lymph node histology compatible with KFD reported in Martinique from 1991 until 2013. In order to describe the characteristics of the disease in a larger cohort, we subsequently included more patients of Afro-Caribbean origin from Guadeloupe and French Guiana.<br />Results: In Martinique, mean annual incidence between 1991 and 2013 was 2.78 cases for 1 million inhabitants (95% confidence interval 1.73-3.93). A total of 36 Afro-Caribbean patients from the 3 French American regions were included. Mean age was 30.5 years (range 5-59 years) and the female:male ratio was 3:1. The main characteristics were cervical adenopathies (88.8%), fever (83.3%), asthenia (73.0%), weight loss (64.4%), and recurrence in 33.3%. KFD was associated with lupus (n = 9 for SLE, n = 2 for cutaneous lupus) in 36.6% (11 of 30).<br />Conclusion: We report the first epidemiologic description of KFD in a population of sub-Saharan origin. According to our data, this disease is present in the black African diaspora and is strongly associated with autoimmune diseases, particularly lupus.<br /> (© 2016, American College of Rheumatology.)
- Subjects :
- Adolescent
Adult
Child
Child, Preschool
Female
France ethnology
Histiocytic Necrotizing Lymphadenitis ethnology
Histiocytic Necrotizing Lymphadenitis etiology
Humans
Incidence
Lupus Erythematosus, Systemic complications
Lupus Erythematosus, Systemic epidemiology
Lupus Erythematosus, Systemic ethnology
Male
Martinique epidemiology
Middle Aged
Retrospective Studies
Young Adult
Black People statistics & numerical data
Histiocytic Necrotizing Lymphadenitis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 2151-4658
- Volume :
- 68
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Arthritis care & research
- Publication Type :
- Academic Journal
- Accession number :
- 27015112
- Full Text :
- https://doi.org/10.1002/acr.22898