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Enhancing panic and smoking reduction treatment with d-cycloserine: Study protocol for a randomized controlled trial.
- Source :
-
Contemporary clinical trials [Contemp Clin Trials] 2016 May; Vol. 48, pp. 46-51. Date of Electronic Publication: 2016 Mar 23. - Publication Year :
- 2016
-
Abstract
- There has been relatively little attention focused on treatment strategies for smokers with panic attacks despite their increased risk of relapse. Panic and Smoking Reduction Treatment (PSRT) integrates standard smoking cessation treatment with an exposure-based intervention targeting the mechanisms underlying panic-smoking relations. Building upon emerging evidence supporting the efficacy of d-cycloserine (DCS) for augmenting exposure-based therapy, we are conducting an initial test of the efficacy of DCS for enhancing PSRT outcomes. Utilizing a randomized, double-blind trial comparing PSRT+DCS to PSRT+placebo, we will obtain initial effect sizes for short-term and long-term smoking cessation outcomes and perform an initial test of putative mechanisms.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1559-2030
- Volume :
- 48
- Database :
- MEDLINE
- Journal :
- Contemporary clinical trials
- Publication Type :
- Academic Journal
- Accession number :
- 27015966
- Full Text :
- https://doi.org/10.1016/j.cct.2016.03.011