Back to Search Start Over

[Basal ganglia germinomas in children. Four clinical cases and a literature review].

Authors :
Konovalov AN
Kadyrov SU
Tarasova EM
Mazerkina NA
Gorelyshev SK
Khukhlaeva EA
Kobyakov GL
Trunin YY
Sanakoeva AV
Kholodov BV
Shishkina LV
Panina TN
Ryzhova MV
Source :
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2016; Vol. 80 (1), pp. 71-82.
Publication Year :
2016

Abstract

Unlabelled: Basal ganglia germinomas are a specific group of intracranial germinomas. Their early diagnosis is complicated due to their atypical localization and diversity of neuroimaging and clinical signs.<br />Material and Methods: We describe 4 cases of basal ganglia germinoma in boys of 13, 14, 15, and 16 years of age. The medical history data, clinical features, neuroimaging and histological characteristics of basal ganglia germonomas, and preliminary results of the treatment are presented.<br />Conclusion: Basal ganglia germinomas are usually verified at the late stage of the disease when patients are detected with extended lesions of the basal ganglia and severe neurological and neuroendocrine deficits. This situation is due to clinical and imaging signs that are untypical of common germinomas.

Details

Language :
English; Russian
ISSN :
0042-8817
Volume :
80
Issue :
1
Database :
MEDLINE
Journal :
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
Publication Type :
Academic Journal
Accession number :
27029333
Full Text :
https://doi.org/10.17116/neiro201680171-82