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A combined computational and experimental investigation of the oxidative ring-opening of cyclic ethers by oxoammonium cations.

Authors :
Loman JJ
Carnaghan ER
Hamlin TA
Ovian JM
Kelly CB
Mercadante MA
Leadbeater NE
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2016 Apr 28; Vol. 14 (16), pp. 3883-8. Date of Electronic Publication: 2016 Mar 31.
Publication Year :
2016

Abstract

The propensity of oxoammonium cations to facilitate the oxidative ring-opening of cyclic ethers to their corresponding distal hydroxy ketones is investigated. The reaction has been evaluated using experimental and computational methods to gain deeper insight into trends in reactivity.

Details

Language :
English
ISSN :
1477-0539
Volume :
14
Issue :
16
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
27031501
Full Text :
https://doi.org/10.1039/c6ob00347h