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The state of melanoma: challenges and opportunities.

Authors :: Merlino G
Herlyn M
Fisher DE
Bastian BC
Flaherty KT
Davies MA
Wargo JA
Curiel-Lewandrowski C
Weber MJ
Leachman SA
Soengas MS
McMahon M
Harbour JW
Swetter SM
Aplin AE
Atkins MB
Bosenberg MW
Dummer R
Gershenwald JE
Halpern AC
Herlyn D
Karakousis GC
Kirkwood JM
Krauthammer M
Lo RS
Long GV
McArthur G
Ribas A
Schuchter L
Sosman JA
Smalley KS
Steeg P
Thomas NE
Tsao H
Tueting T
Weeraratna A
Xu G
Lomax R
Martin A
Silverstein S
Turnham T
Ronai ZA
Source :: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2016 Jul; Vol. 29 (4), pp. 404-16. Date of Electronic Publication: 2016 Apr 17.
Publication Year :: 2016
Abstract: The Melanoma Research Foundation (MRF) has charted a comprehensive assessment of the current state of melanoma research and care. Intensive discussions among members of the MRF Scientific Advisory Council and Breakthrough Consortium, a group that included clinicians and scientists, focused on four thematic areas - diagnosis/early detection, prevention, tumor cell dormancy (including metastasis), and therapy (response and resistance). These discussions extended over the course of 2015 and culminated at the Society of Melanoma Research 2015 International Congress in November. Each of the four groups has outlined their thoughts as per the current status, challenges, and opportunities in the four respective areas. The current state and immediate and long-term needs of the melanoma field, from basic research to clinical management, are presented in the following report.<br /> (© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)