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Enteral nutrition versus parenteral nutrition after major abdominal surgery in patients with gastrointestinal cancer: a systematic review and meta-analysis.
Enteral nutrition versus parenteral nutrition after major abdominal surgery in patients with gastrointestinal cancer: a systematic review and meta-analysis.
- Source :
-
Journal of investigative medicine : the official publication of the American Federation for Clinical Research [J Investig Med] 2016 Jun; Vol. 64 (5), pp. 1061-74. Date of Electronic Publication: 2016 Apr 25. - Publication Year :
- 2016
-
Abstract
- To clarify the benefits of enteral nutrition (EN) versus total parenteral nutrition (TPN) in patients with gastrointestinal cancer who underwent major abdominal surgery. Medline, Cochrane, EMBASE, and Google Scholar were searched for studies published until July 10, 2015, reporting outcomes between the two types of postoperative nutritional support. Only randomized controlled trials (RCTs) were included. A χ(2)-based test of homogeneity was performed using Cochran's Q statistic and I(2) A total of 2540 patients (1268 who received EN and 1272 who received TPN; average age range: 58.3-67.7 years) from 18 RCTs were included for assessment. Patients who received EN had shorter lengths of hospital stay (pooled difference in mean=-1.74, 95% CI -2.41 to -1.07, p<0.001, shorter time to flatus (pooled difference in mean=-1.27, 95% CI -1.69 to -0.85, p<0.001), and significantly greater increases in albumin levels (pooled difference in mean=-1.33, 95% CI -2.18 to -0.47, p=0.002) compared with those who received TPN after major abdominal surgery, based on a random-effects model of analysis. EN after major abdominal surgery provided better outcomes compared with TPN in patients with gastrointestinal cancer.<br /> (Copyright © 2016 American Federation for Medical Research.)
- Subjects :
- Anastomotic Leak etiology
Gastrointestinal Neoplasms blood
Gastrointestinal Neoplasms mortality
Humans
Length of Stay
Outcome Assessment, Health Care
Postoperative Complications etiology
Publication Bias
Quality Assurance, Health Care
Sensitivity and Specificity
Serum Albumin metabolism
Abdomen surgery
Enteral Nutrition mortality
Gastrointestinal Neoplasms surgery
Gastrointestinal Neoplasms therapy
Parenteral Nutrition mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1708-8267
- Volume :
- 64
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of investigative medicine : the official publication of the American Federation for Clinical Research
- Publication Type :
- Academic Journal
- Accession number :
- 27112357
- Full Text :
- https://doi.org/10.1136/jim-2016-000083