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Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients.
- Source :
-
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [S Afr Med J] 2016 Apr 19; Vol. 106 (5), pp. 35-6. Date of Electronic Publication: 2016 Apr 19. - Publication Year :
- 2016
-
Abstract
- The polymyxin antibiotic colistin is an antibiotic of last resort for the treatment of extensively drug-resistant Gram-negative bacteria, including carbapenemase-producing Enterobacteriaceae. The State of the World's Antibiotics report in 2015 highlighted South Africa (SA)'s increasing incidence of these 'superbugs' (3.2% of Klebsiella pneumoniae reported from SA were carbapenemase producers), and in doing so, underscored SA's increasing reliance on colistin as a last line of defence. Colistin resistance effectively renders such increasingly common infections untreatable.
Details
- Language :
- English
- ISSN :
- 0256-9574
- Volume :
- 106
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 27138657
- Full Text :
- https://doi.org/10.7196/SAMJ.2016.v106i5.10710