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Total arterial grafting is associated with improved clinical outcomes compared to conventional myocardial revascularization at 10 years follow-up.
- Source :
-
Heart and vessels [Heart Vessels] 2017 Feb; Vol. 32 (2), pp. 109-116. Date of Electronic Publication: 2016 May 03. - Publication Year :
- 2017
-
Abstract
- The use of arterial conduits is associated with incremental benefits when compared to conventional CABG surgery, albeit there is a paucity of data regarding the long-term outcomes of either techniques. Among 973 consecutive patients undergoing CABG, a propensity-match study was performed to compare total arterial revascularization technique (G1) with a conventional approach (LITA on LAD plus additional SVGs, G2). The study population was propensity-matched based on preoperative characteristics (age, sex, risk factors). Mean number of grafted vessels (G1 = 2.39 ± 0.55 vs G2 = 2.37 ± 0.7; p = 0.79) and aortic cross-clamp time (G1 = 36 ± 6 vs G2 = 35 ± 6 min; p = 0.31) were similar while CPB time was significantly longer in Group 2 (G1 = 50 ± 7 vs G2 = 70 ± 8 min; p = 0.03). Hospital mortality (G1 = 0.6 % vs G2 = 1.3 %; p = 0.41) and overall incidence of postoperative complications were also comparable. Cox regression analysis depicted conventional CABG as an independent predictor for MACCEs (HR = 4.53, CI 95 % = 2-10.28; p < 0.001). Median follow-up time was 112 months: actuarial survival free from cardiac death (G1 = 100 % vs G2 = 95 ± 2.1 %; p = 0.046) and MACCEs (G1 = 97.3 ± 1.5 % vs G2 = 79.4 ± 3.8 %; p < 0.001) was significantly improved in patients undergoing total arterial grafting. Total arterial myocardial revascularization is associated with significantly improved outcomes at 10 years follow-up in terms of cardiac-related mortality and overall event-free survival.
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Follow-Up Studies
Hospital Mortality
Humans
Italy
Male
Middle Aged
Multivariate Analysis
Postoperative Complications epidemiology
Propensity Score
Regression Analysis
Risk Factors
Survival Analysis
Treatment Outcome
Coronary Artery Bypass methods
Saphenous Vein transplantation
Subjects
Details
- Language :
- English
- ISSN :
- 1615-2573
- Volume :
- 32
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Heart and vessels
- Publication Type :
- Academic Journal
- Accession number :
- 27142066
- Full Text :
- https://doi.org/10.1007/s00380-016-0846-6