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Excited State Pathways Leading to Formation of Adenine Dimers.

Authors :
Banyasz A
Martinez-Fernandez L
Ketola TM
Muñoz-Losa A
Esposito L
Markovitsi D
Improta R
Source :
The journal of physical chemistry letters [J Phys Chem Lett] 2016 Jun 02; Vol. 7 (11), pp. 2020-3. Date of Electronic Publication: 2016 May 18.
Publication Year :
2016

Abstract

The reaction intermediate in the path leading to UV-induced formation of adenine dimers A═A and AA* is identified for the first time quantum mechanically, using PCM/TD-DFT calculations on (dA)2 (dA: 2'deoxyadenosine). In parallel, its fingerprint is detected in the absorption spectra recorded on the millisecond time-scale for the single strand (dA)20 (dA: 2'deoxyadenosine).

Details

Language :
English
ISSN :
1948-7185
Volume :
7
Issue :
11
Database :
MEDLINE
Journal :
The journal of physical chemistry letters
Publication Type :
Academic Journal
Accession number :
27163876
Full Text :
https://doi.org/10.1021/acs.jpclett.6b00660