Changes in Corneal Thickness and Specular Microscopic Indices in Acute Unilateral Anterior Uveitis.

Purpose: To compare central corneal thickness (CCT) and specular microscopic indices in active unilateral anterior uveitis with the same indices 1 week after the initiation of treatment.
Methods: This study included 30 eyes with active unilateral idiopathic anterior uveitis. CCT and specular microscopic indices were compared before and after 1 week of the treatment with topical medications.
Results: At the first visit, mean CCT was significantly greater in affected eyes (mean ± standard deviation: 514.0 ± 23.0) than in fellow eyes (493.2 ± 10.6) (p < 05). There was a significant decrease in CCT of the involved eye 1 week after start of treatment to 494.1 ± 23.1 μm (p < 05). No significant differences were observed in the specular microscopic indices between the affected and fellow eyes before treatment and 1 week after the treatment.
Conclusion: We found that eyes with unilateral active anterior uveitis had increased CCT in comparison to their healthy fellow eyes without a change in the specular microscopic indices.