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Lipid peroxidation and superoxide dismutase activity in muscle and erythrocytes in adult muscular dystrophies and neurogenic atrophies.
- Source :
-
European archives of psychiatry and neurological sciences [Eur Arch Psychiatry Neurol Sci] 1989; Vol. 238 (3), pp. 175-7. - Publication Year :
- 1989
-
Abstract
- Lipid peroxidation (LP) and superoxide dismutase (SOD) activity were determined in erythrocytes and skeletal muscle obtained from patients with limb-girdle and facioscapulohumeral muscular dystrophies, neurogenic atrophies and from age-matched control subjects. Neither lipid peroxidation nor SOD activity in erythrocytes of patients differed from control values. SOD activity and LP in muscle specimens were also normal in types of neurogenic atrophy. Lipid peroxidation in the muscle from patients with adult types of muscular dystrophy had a tendency to be increased. The values were widely scattered, the highest being obtained in the older patients with long duration of disease.
- Subjects :
- Adult
Amyotrophic Lateral Sclerosis enzymology
Female
Humans
Male
Middle Aged
Muscles innervation
Muscular Atrophy, Spinal enzymology
Erythrocytes enzymology
Lipid Peroxidation
Motor Neurons physiology
Muscles enzymology
Muscular Dystrophies enzymology
Neuromuscular Diseases enzymology
Superoxide Dismutase blood
Subjects
Details
- Language :
- English
- ISSN :
- 0175-758X
- Volume :
- 238
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- European archives of psychiatry and neurological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 2721536
- Full Text :
- https://doi.org/10.1007/BF00451007